Learn More
Bcl-XL Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 107831AP150UL

Description
This antibody can recognize Bcl-XL, Bcl-X (s) and Bcl-X(Beta).
BCL-XL is a part of the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL-XL is located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential and controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.Specifications
Bcl-XL | |
Polyclonal | |
Unconjugated | |
BCL2L1 | |
Apoptosis regulator Bcl X, BCL2L1, Bcl-XL | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
12048, 24888, 598 | |
-20°C | |
Liquid |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation | |
0.23 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P53563, Q07817, Q64373 | |
BCL2L1 | |
Bcl-XL Fusion Protein Ag1232 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.