BCL11A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-7310	Proteintech Group Inc 116131AP150UL	150 μL

Description

This is a rabbit polyclonal antibody raised against part chain of N-terminal BCL11A of human origin. There are three isoforms of BCL11A: isoform1 (773 aa), isoform2 (486 aa), and isoform3 (239 aa).

This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell maligcies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.

Specifications

• Antigen: BCL11A
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q9H165, Q9QYE3
• Gene ID (Entrez): 14025, 305589, 53335
• Immunogen: BCL11A Fusion Protein Ag2187
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: BCL11A

• Concentration: 0.19 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: B cell CLL/lymphoma 11A, B cell lymphoma/leukemia 11A, BCL11A, COUP TF interacting protein 1, CTIP1, EVI 9, EVI9, HBFQTL5, KIAA1809, ZNF856
• Gene Symbols: BCL11A
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody