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beta 2-Microglobulin Antibody (246-E9.E7 (same as HLA.ABC.m2)), Alexa Fluor™ 532, Novus Biologicals™
SDP

Catalog No. NP24770A532 Shop All R&D Systems Products
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NP24770A532 0.1 mL
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Catalog No. NP24770A532 Supplier Novus Biologicals Supplier No. NBP247700AF532
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Description

Mouse Monoclonal Antibody

beta 2-Microglobulin Monoclonal specifically detects beta 2-Microglobulin in Human, Primate (Negative) samples. It is validated for Flow Cytometry, Immunofluorescence.

Specifications

Antigen beta 2-Microglobulin
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone 246-E9.E7 (same as HLA.ABC.m2)
Conjugate Alexa Fluor 532
Dilution Flow Cytometry, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Gene Symbols B2M
Host Species Mouse
Immunogen Human PBL s from a T-cell acute lymphoblastic leukemia (T-ALL) patient.
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 567.0
Test Specificity Recognizes a protein of 12kDa, identified as beta-microglobulin. Beta--microglobulin non-covalently associates with the 44kDa chain to form the HLA Class I antigen complex. Human beta-2 microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This monoclonal antibody is specific to human beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. Detection of beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.
Target Species Human, Primate
Content And Storage Store at 4°C in the dark.
Isotype IgG2a κ
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