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beta 2-Microglobulin Antibody (246-E9.E7 (same as HLA.ABC.m2)) - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. NBP247700A Shop All R&D Systems Products
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0.2 mg
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NBP247700A 0.1 mg
NBP247700B 0.2 mg
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Catalog No. NBP247700A Supplier Novus Biologicals Supplier No. NBP2477000.1MG
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Mouse Monoclonal Antibody

beta 2-Microglobulin Monoclonal specifically detects beta 2-Microglobulin in Human, Primate (Negative) samples. It is validated for Flow Cytometry, Immunofluorescence, CyTOF-ready.

Specifications

Antigen beta 2-Microglobulin
Applications Flow Cytometry, Immunofluorescence, CyTOF
Classification Monoclonal
Clone 246-E9.E7 (same as HLA.ABC.m2)
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Gene Symbols B2M
Host Species Mouse
Immunogen Human PBL s from a T-cell acute lymphoblastic leukemia (T-ALL) patient.
Molecular Weight of Antigen 12 kDa
Purification Method Protein A or G purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 567
Test Specificity Recognizes a protein of 12kDa, identified as beta-microglobulin. beta-microglobulin non-covalently associates with the 44kDa chain to form the HLA Class I antigen complex. Human beta-2 microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.
Target Species Human, Primate (Negative)
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG2a κ
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