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beta 2-Microglobulin Antibody (B2M/1118), Alexa Fluor™ 594, Novus Biologicals™
SDP

Catalog No. NP247702A94 Shop All R&D Systems Products
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Catalog No. NP247702A94 Supplier Novus Biologicals Supplier No. NBP247702AF594
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Description

Mouse Monoclonal Antibody

beta 2-Microglobulin Monoclonal specifically detects beta 2-Microglobulin in Human, Primate samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence.

Specifications

Antigen beta 2-Microglobulin
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone B2M/1118
Conjugate Alexa Fluor 594
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Gene Symbols B2M
Host Species Mouse
Immunogen Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769)
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 567
Test Specificity beta 2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta 2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin′s lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. beta 2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).
Target Species Human, Primate
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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