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beta 2-Microglobulin Antibody (B2M/1118) - Azide and BSA Free, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP2477020.2MG
Description
beta 2-Microglobulin Monoclonal antibody specifically detects Antigen in Human, Primate samples. It is validated for Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin).Specifications
beta 2-Microglobulin | |
Monoclonal | |
1.0 mg/mL | |
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Flow (Cell Surface) 1:10-1:1000, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready | |
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin | |
Mouse | |
12 kDa | |
0.2 mg | |
Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology | |
567 | |
Human, Primate | |
Purified |
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF | |
B2M/1118 | |
Unconjugated | |
PBS with No Preservative | |
B2M | |
Full length recombinant human B2M protein | |
Protein A or G purified | |
RUO | |
Primary | |
beta 2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta 2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. beta 2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy). | |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | |
IgG1 κ |
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