beta-Catenin Antibody (9F2), Alexa Fluor™ 532, Novus Biologicals™

Catalog No.	Quantity
NP2449A32	0.1 mL

Catalog No. NP2449A32 Supplier Novus Biologicals Supplier No. NBP254495AF532

Description

Mouse Monoclonal Antibody

beta-Catenin Monoclonal specifically detects beta-Catenin in Human, Bovine, Canine, Chicken samples. It is validated for Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Specifications

• Antigen: beta-Catenin
• Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
• Classification: Monoclonal
• Clone: 9F2
• Conjugate: Alexa Fluor 532
• Dilution: Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Alias: beta 1 (88kD), beta-catenin, catenin (cadherin-associated protein), beta 1, 88kDa, catenin beta-1, CTNNB, DKFZp686D02253, FLJ25606, FLJ37923
• Gene Symbols: CTNNB1
• Host Species: Mouse
• Immunogen: Recombinant chicken beta-Catenin (Uniprot: P35222)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Gene ID (Entrez): 1499
• Test Specificity: This monoclonal antibody recognizes a protein of 92kDa, which is identified as beta-catenin. It shows no cross-reaction with gamma-catenin (also known as plakoglobin). The catenins, alpha, beta and gamma bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin was initially described as an E-cadherin-associated protein, and has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin has also been found in complexes with the tumor suppressor protein APC.
• Target Species: Human, Bovine, Canine, Chicken
• Content And Storage: Store at 4°C in the dark.
• Isotype: IgG1 κ