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Invitrogen™ Biliverdin Reductase Polyclonal Antibody

Rabbit Polyclonal Antibody

$237.00 - $539.50

Specifications

Antigen Biliverdin Reductase
Concentration 500 μg/mL
Content And Storage -20°C
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
PIPA5118982
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Invitrogen™
PA5118982
200 μL
Each for $539.50
Only null left
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PIPA5122199
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Invitrogen™
PA5122199
20 μL
Each for $237.00
Only null left
Add to Cart
 
Description

Description

Biliverdin Reductase Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

Biliverdin reductase (BLVR) is a ubiquitously expressed, small cytoplasmic oxidoreductase that catalyzes the reduction of biliverdin to bilirubin. The first step of this process is catalyzed by heme oxygenase, an enzyme that converts heme to iron, carbon monoxide, and biliverdin. BLVR is unique among all enzymes to date in being dual pH/dual cofactor-dependent, as it requires NADH (pH 6.7) or NADPH (pH 8.7) as an electron donor. There are two isoforms of BLVR, biliverdin-IX alpha-reductase (BLVRA), the major component of human adult liver, and biliverdin-IX beta-reductase (BLVRB), found predominantly in fetal liver. The product of BLVR, bilirubin, is an important biological antioxidant, however it is also a neurotoxin and the cause of kernicterus. In addition to being an antioxidant, it inhibits kinase activity and the activity of enzymes such as protein kinase C and NADPH oxidase.
Specifications

Specifications

Biliverdin Reductase
-20°C
Polyclonal
Liquid
IgG
Rat
Blvra
0610006A11Rik; 2500001N03Rik; Biliverdin reductase A; biliverdin reductase A-like protein; biliverdin-IX alpha-reductase; BLVR; Blvra; BVR; BVR A; BVRA; EC 1.3.1.24; testis tissue sperm-binding protein Li 61n
Blvra
Primary
Antigen affinity chromatography
500 μg/mL
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Unconjugated
Rabbit
RUO
PBS with 50% glycerol and 0.05% ProClin 300
P46844
116599
Recombinant protein Biliverdin Reductase A. The antigen corresponds to amino acid range 10-279 of the target protein.
Antibody
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