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Invitrogen™ Biliverdin Reductase Polyclonal Antibody
Rabbit Polyclonal Antibody
$237.00 - $539.50
Specifications
Antigen | Biliverdin Reductase |
---|---|
Concentration | 500 μg/mL |
Content And Storage | -20°C |
Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
Classification | Polyclonal |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
PIPA5118982
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Invitrogen™
PA5118982 |
200 μL |
Each for $539.50
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PIPA5122199
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Invitrogen™
PA5122199 |
20 μL |
Each for $237.00
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Description
Biliverdin Reductase Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)
Biliverdin reductase (BLVR) is a ubiquitously expressed, small cytoplasmic oxidoreductase that catalyzes the reduction of biliverdin to bilirubin. The first step of this process is catalyzed by heme oxygenase, an enzyme that converts heme to iron, carbon monoxide, and biliverdin. BLVR is unique among all enzymes to date in being dual pH/dual cofactor-dependent, as it requires NADH (pH 6.7) or NADPH (pH 8.7) as an electron donor. There are two isoforms of BLVR, biliverdin-IX alpha-reductase (BLVRA), the major component of human adult liver, and biliverdin-IX beta-reductase (BLVRB), found predominantly in fetal liver. The product of BLVR, bilirubin, is an important biological antioxidant, however it is also a neurotoxin and the cause of kernicterus. In addition to being an antioxidant, it inhibits kinase activity and the activity of enzymes such as protein kinase C and NADPH oxidase.Specifications
Biliverdin Reductase | |
-20°C | |
Polyclonal | |
Liquid | |
IgG | |
Rat | |
Blvra | |
0610006A11Rik; 2500001N03Rik; Biliverdin reductase A; biliverdin reductase A-like protein; biliverdin-IX alpha-reductase; BLVR; Blvra; BVR; BVR A; BVRA; EC 1.3.1.24; testis tissue sperm-binding protein Li 61n | |
Blvra | |
Primary | |
Antigen affinity chromatography |
500 μg/mL | |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
Unconjugated | |
Rabbit | |
RUO | |
PBS with 50% glycerol and 0.05% ProClin 300 | |
P46844 | |
116599 | |
Recombinant protein Biliverdin Reductase A. The antigen corresponds to amino acid range 10-279 of the target protein. | |
Antibody |
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