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Invitrogen™ BMP-10 Polyclonal Antibody
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Catalog No. PIPA521940
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Quantity:
100 μL
Catalog No. Quantity
PIPA521940 100 μL
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Catalog No. PIPA521940

Supplier: Invitrogen™ PA521940

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: H1299. Predicted reactivity: Mouse (100%), Rat (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. BMP-10 plays a crucial role in the development of the embryonic heart by acting to stimulate and maintain cardiomyocyte proliferation. It can signal through various receptor complexes usually containing BMPR-1A, BMPR-1B, ALK1, ALK3, or ALK6. The interaction of BMP-10 with its specific receptors can induce signaling initiated by the phosphorylation of SMAD transcription factors, including SMAD1, SMAD5, or SMAD8, but can also induce SMAD independent processes. BMP-10 is structurally related to BMP-9, and both can inhibit endothelial cell proliferation and migration.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BMP-10
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.51 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene BMP10
Gene Accession No. O95393
Gene Alias BMP; BMP10; BMP-10; bmp10 {ECO:0000312; bmp10b; Bone morphogenetic protein; bone morphogenetic protein 10; EMBL:BAE16990.1, ECO:0000312; RGD:1562986}; si:dkey-13n15.5
Gene Symbols BMP10
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human BMP10. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27302
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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