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R&D Systems™ BMS 299897
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Catalog No. 287010 Shop All Novus Products
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Catalog No. Quantity
28-701-0 10 mg
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Catalog No. 28-701-0 Supplier R&D Systems™ Supplier No. 2870/10

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A Tocris product, part of R&D Systems. Potent γ-secretase inhibitor

Orally active, potent γ-secretase inhibitor (IC50 = 12 nM). Inhibits Aβ40 and Aβ42 formation in vitro (IC50 values are 7.4 and 7.9 nM respectively) and reduces Aβ in the brain, plasma and cerebrospinal fluid in vivo. Exhibits no Notch toxicity. Brain penetrant.

Chemical Identifiers

CAS 290315-45-6
Molecular Formula C24H21ClF3NO4S

Specifications

Quantity 10 mg
Product Line Tocris
Formula Weight 511.94
Purity >98%
Molecular Weight (g/mol) 511.94
Chemical Name or Material BMS 299897
Recommended Storage Store at -20°C
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