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Tocris Bioscience™ BMS 299897
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Catalog No. 287010
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10 mg
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Catalog No. Quantity
28-701-0 10 mg
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Catalog No. 28-701-0 Supplier Tocris Bioscience™ Supplier No. 2870/10
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Description

Potent γ-secretase inhibitor

Orally active, potent γ-secretase inhibitor (IC50 = 12 nM). Inhibits Aβ40 and Aβ42 formation in vitro (IC50 values are 7.4 and 7.9 nM respectively) and reduces Aβ in the brain, plasma and cerebrospinal fluid in vivo. Exhibits no Notch toxicity. Brain penetrant.

Chemical Identifiers

CAS 290315-45-6
Molecular Formula C24H21ClF3NO4S

Specifications

Quantity 10 mg
Formula Weight 511.94
Purity >98%
Molecular Weight (g/mol) 511.94
Chemical Name or Material BMS 299897

Safety and Handling

Recommended Storage Store at -20°C
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