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BMS 299897, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
This item is not returnable. View return policy
290315-45-6
C24H21ClF3NO4S
511.94
IZAOBRWCUGOKNH-OAHLLOKOSA-N
2-1r-1-4-chlorophenyl sulfonyl 2,5-difluorophenyl amino ethyl-5-fluoro-benzenebutanoic acid,2-1r-1-4-chlorophenyl sulfonyl 2,5-difluorophenyl amino ethyl-5-fluorobenzenebutanoic acid,2-1r-1-4-chlorophenyl sulfonyl 2,5-difluorophenyl amino ethyl-5-fluorobenzenebutanoic acid,4-2-1r-1-n-2,5-difluorophenyl 4-chlorobenzenesulfonamido ethyl-5-fluorophenyl butanoic acid,2-1r-1-4-chlorophenyl sulfonyl 2,5-difluorophenyl amino ethyl-5-fluorobenzenebutanoic acid
11249248
4-[2-[(1R)-1-(N-(4-chlorophenyl)sulfonyl-2,5-difluoroanilino)ethyl]-5-fluorophenyl]butanoic acid
CC(C1=C(C=C(C=C1)F)CCCC(=O)O)N(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl
This item is not returnable. View return policy
290315-45-6
C24H21ClF3NO4S
511.94
IZAOBRWCUGOKNH-OAHLLOKOSA-N
2-1r-1-4-chlorophenyl sulfonyl 2,5-difluorophenyl amino ethyl-5-fluoro-benzenebutanoic acid,2-1r-1-4-chlorophenyl sulfonyl 2,5-difluorophenyl amino ethyl-5-fluorobenzenebutanoic acid,2-1r-1-4-chlorophenyl sulfonyl 2,5-difluorophenyl amino ethyl-5-fluorobenzenebutanoic acid,4-2-1r-1-n-2,5-difluorophenyl 4-chlorobenzenesulfonamido ethyl-5-fluorophenyl butanoic acid,2-1r-1-4-chlorophenyl sulfonyl 2,5-difluorophenyl amino ethyl-5-fluorobenzenebutanoic acid
11249248
4-[2-[(1R)-1-(N-(4-chlorophenyl)sulfonyl-2,5-difluoroanilino)ethyl]-5-fluorophenyl]butanoic acid
CC(C1=C(C=C(C=C1)F)CCCC(=O)O)N(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl

Potent γ-secretase inhibitor

Orally active, potent γ-secretase inhibitor (IC 50 = 12 nM). Inhibits Aβ40 and Aβ42 formation in vitro (IC 50 values are 7.4 and 7.9 nM respectively) and reduces Aβ in the brain, plasma and cerebrospinal fluid in vivo. Exhibits no Notch toxicity. Brain penetrant.

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Quantity 10mg
Formula Weight 511.94
Percent Purity >98%
Chemical Name or Material BMS 299897

Recommended Storage : Store at -20°C