Tocris™ BMS 345541

Selective allosteric inhibitor of IKK; anti-inflammatory

Manufacturer: Tocris™ 4806/10

 View more versions of this product

Catalog No. 48-061-0

  Check Availability
Add to Cart

Disclaimers:

For Research Use Only


    Specifications

    Product Type BMS 345541
    Inhibitors BMS 345541
    Purity >99
    Molecular Weight 291.78
    Quantity 10mg

    Selective allosteric inhibitor of IKK (IC50 values are 0.3 and 4.0µM for IKKβ and IKKα respectively). Exhibits no effect against a panel of 15 other kinases. Attenuates LPS-induced cytokine production in vitro and blocks NFκB dependent transcription in mice. Also suppresses joint destruction in a mouse model of arthritis.

    • Chemical Name: N1-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine hydrochloride
    • Formula: C14H17N5.HCl
    • CAS Number: 547757-23-3
    • Solubility: Soluble to 100mM in water and to 100mM in DMSO
    • Purity: >99

  • Description & Specifications

Related Products


Product Content Feedback

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit