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BMS 986187, >98%, Tocris Bioscience™

Potent δ-opioid receptor positive allosteric modulator

Supplier:  R&D Systems 5983/50

Quantity 50 mg

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Catalog No. 59-835-0


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Description

Description

Potent δ-opioid receptor positive allosteric modulator (EC50 = 30 nM). Exhibits 100-fold selectivity for δ over μ-opioid receptor. Enhances affinity of [Leu5]-Enkephalin (Cat.No. 1889), SNC 80 (Cat.No. 0764) and TAN 67 (Cat.No. 0921) for the δ-opioid receptor.
Specifications

Chemical Identifiers

684238-37-7
470.609
3,3,6,6-tetramethyl-9-4-2-methylbenzyl oxy phenyl-3,4,5,6,7,9-hexahydro-1h-xanthene-1,8 2h-dione, 3,3,6,6-tetramethyl-9-4-2-methylbenzyloxy phenyl-3,4,5,6-tetrahydro-9h-xanthene-1 2h ,8 7h-dione, 3,3,6,6-tetramethyl-9-4-2-methylphenyl methoxy phenyl-4,5,7,9-tetrahydro-2h-xanthene-1,8-dione, 3,4,5,6,7,9-hexahydro-3,3,6,6-tetramethyl-9-4-2-methylphenyl methoxy phenyl-1h-xanthene-1,8 2h-dione
3,3,6,6-tetramethyl-9-[4-[(2-methylphenyl)methoxy]phenyl]-4,5,7,9-tetrahydro-2H-xanthene-1,8-dione
C31H34O4
UEKIYVKPQNKSDI-UHFFFAOYSA-N
17379334
CC1=CC=CC=C1COC2=CC=C(C=C2)C3C4=C(CC(CC4=O)(C)C)OC5=C3C(=O)CC(C5)(C)C

Specifications

684238-37-7
C31H34O4
3,3,6,6-tetramethyl-9-4-2-methylbenzyl oxy phenyl-3,4,5,6,7,9-hexahydro-1h-xanthene-1,8 2h-dione, 3,3,6,6-tetramethyl-9-4-2-methylbenzyloxy phenyl-3,4,5,6-tetrahydro-9h-xanthene-1 2h ,8 7h-dione, 3,3,6,6-tetramethyl-9-4-2-methylphenyl methoxy phenyl-4,5,7,9-tetrahydro-2h-xanthene-1,8-dione, 3,4,5,6,7,9-hexahydro-3,3,6,6-tetramethyl-9-4-2-methylphenyl methoxy phenyl-1h-xanthene-1,8 2h-dione
UEKIYVKPQNKSDI-UHFFFAOYSA-N
3,3,6,6-tetramethyl-9-[4-[(2-methylphenyl)methoxy]phenyl]-4,5,7,9-tetrahydro-2H-xanthene-1,8-dione
17379334
3,4,5,6,7,9-Hexahydro-3,3,6,6-tetramethyl-9-[4-[(2-methylphenyl)methoxy]phenyl]-1H-xanthene-1,8(2H)-
C31H34O4
50 mg
Soluble to 20mM in DMSO
CC1=CC=CC=C1COC2=CC=C(C=C2)C3C4=C(CC(CC4=O)(C)C)OC5=C3C(=O)CC(C5)(C)C
470.609
470.61
>98%
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