BRAF Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-157-2394	Bethyl Laboratories, Inc IHC00607T	10 μL
50-157-2393	Bethyl Laboratories, Inc IHC00607	100 μL

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, Dog, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Small-eared galago a

B-raf belongs to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in the gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, maligt melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Specifications

• Antigen: BRAF
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: B-Raf proto-oncogene serine/threonine-protein kinase; p94; v-Raf murine sarcoma viral oncogene homolog B1; BRAF; BRAF1; RAFB1;
• Gene Symbols: BRAF
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody

• Applications: Immunohistochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: P15056
• Gene ID (Entrez): 673
• Immunogen: Between 25 and 75
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: BRAF