Thermo Scientific™ BS3 (bis(sulfosuccinimidyl)suberate)

Description

Crosslink amines to amines with BS3; composed of sulfo-NHS-ester groups separated by an 11.4A, water-soluble spacer arm that is useful for cell-surface protein crosslinking.

Thermo Scientific™ Pierce BS3 (Sulfo-DSS) is bis(sulfosuccinimidyl)suberate, an amine-to-amine crosslinker that is homobifunctional, water-soluble, non-cleavable and membrane impermeable.

• Reactive groups: sulfo-NHS ester (both ends)
• Reactive towards: amino groups (primary amines)
• Amine-reactive Sulfo-NHS ester reacts rapidly with any primary amine-containing molecule
• Water-soluble; compare with DSS
• Membrane-impermeable, allowing for cell surface labeling
• High-purity, crystalline reagent can be used to create high-purity crosslinked conjugates

Specifications

• Chemical Reactivity: Amine-Amine
• Cleavable: No
• Molecular Weight (g/mol): 572.43
• PEGylated: No
• Spacer Arm Length: 11.4 Å
• Content And Storage: Upon receipt store desiccated at 4°C.
• Cell Permeability: No
• Shipping Condition: Ambient
• Product Line: No-Weigh™, Pierce™
• Labeling Method: Chemical Labeling
• Crosslinker Type: Homobifunctional
• Reactive Moiety: Sulfo-NHS Ester
• Spacer: Medium (10 to 30 Å)
• Form: Solid
• Quantity: 10 x 2 mg
• Solubility: Water
• Format: Standard, Single-use, Premium-grade
• Water Soluble: Yes
• Product Type: Crosslinker

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov

For Research Use Only. Not for use in diagnostic procedures.