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CA19-9/Sialyl Lewis A Antibody (CA19.9/1390R), Alexa Fluor™ 750, Novus Biologicals™
SDP

Catalog No. NP248A70 Shop All R&D Systems Products
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Catalog No. NP248A70 Supplier Novus Biologicals Supplier No. NBP254585AF750
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Description

Rabbit Monoclonal Antibody

CA19-9/Sialyl Lewis A Monoclonal specifically detects CA19-9/Sialyl Lewis A in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen CA19-9/Sialyl Lewis A
Applications Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone CA19.9/1390R
Conjugate Alexa Fluor 750
Dilution Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Formulation 50 mM sodium borate with 0.05% sodium azide
Host Species Rabbit
Immunogen Purified human CA19-9 protein
Quantity 0.1 mL
Primary or Secondary Primary
Test Specificity CA19-9, a carbohydrate epitope expressed on a high MW (400kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This monoclonal antibody is excellent for staining of formalin-fixed, paraffin-embedded tissues.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG
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