CACNB4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-1781	Proteintech Group Inc 177701AP150UL	150 μL

Description

This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy and juvenile myoclonic epilepsy. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: CACNB4
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: D4A055, O00305, Q8R0S4
• Gene ID (Entrez): 12298, 58942, 785
• Immunogen: CACNB4 Fusion Protein Ag12178
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: CACNB4

• Concentration: 0.16 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: CAB4, CACNB4, CACNLB4, EA5, EJM
• Gene Symbols: Cacnb4
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody