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Cadherin-16 Antibody (SPM594), Alexa Fluor™ 350, Novus Biologicals™
SDP

Catalog No. NP247746A30 Shop All R&D Systems Products
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NP247746A30 0.1 mL
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Catalog No. NP247746A30 Supplier Novus Biologicals Supplier No. NBP247746AF350
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Description

Mouse Monoclonal Antibody

Cadherin-16 Monoclonal specifically detects Cadherin-16 in Human, Mouse, Rat, Canine, Rabbit samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Cadherin-16
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SPM594
Conjugate Alexa Fluor 350
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias cadherin 16, KSP-cadherin, cadherin-16, Kidney-specific cadherin, KSP-cadherin
Gene Symbols CDH16
Host Species Mouse
Immunogen Recombinant full-length human Cadherin-16 protein (Uniprot: O75309)
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 1014
Test Specificity This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Target Species Human, Mouse, Rat, Canine, Rabbit
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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