Cadherin-16 Antibody (SPM594), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2451580.02MG

Catalog No. NBP24515800

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin)

Cadherin-16 Monoclonal specifically detects Cadherin-16 in Human, Mouse, Rat, Canine, Rabbit samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Cadherin-16
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
• Gene Accession No.: O75309
• Gene Symbols: CDH16
• Immunogen: Recombinant human CDH16 protein
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Gene ID (Entrez): 1014
• Target Species: Human, Mouse, Rat, Canine, Rabbit
• Form: Purified

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
• Clone: SPM594
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Alias: cadherin 16, KSP-cadherin, cadherin-16, Kidney-specific cadherin, KSP-cadherin
• Host Species: Mouse
• Molecular Weight of Antigen: 130 kDa
• Quantity: 0.02 mg
• Primary or Secondary: Primary
• Test Specificity: This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ

For Research Use Only