Cadherin-18 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-8481	Proteintech Group Inc 130911AP150UL	150 μL

Description

This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Specifications

• Antigen: Cadherin-18
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q13634
• Gene ID (Entrez): 1016
• Immunogen: Cadherin-18 Fusion Protein Ag3675
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: CDH18

• Concentration: 0.39 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: cadherin 18, type 2, Cadherin-14, Cadherin-18, CDH14, CDH14L, CDH18, EY CADHERIN
• Gene Symbols: CDH18
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody