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Epredia™ Lab Vision™ Cadherin-P Ab-1, Mouse Monoclonal Antibody

Catalog No. MS1741S0 Shop All Epredia Products
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100 μL
500 μL
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7 mL
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Supernatant
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Catalog No. Quantity Form
MS1741S0 100 μL Supernatant
MS1741R7 7 mL Prediluted
MS1741S1 500 μL Supernatant
MS1741S 1 mL Supernatant
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Catalog No. MS1741S0 Supplier Epredia™ Supplier No. MS1741S0

Description

Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ Cadherin-P Ab-1, Mouse Monoclonal Antibody.

Cadherins are calcium dependent cell adhesion molecules, which play important roles in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. They are expressed in a tissue specific manner and are required for assembly of cells into solid tissue. Individual cadherin molecules are known to cooperate with each other to form a linear cell adhesion zipper. In adhesion junctions cadherins are bound to Beta and gamma catenins which in turn bind to alpha catenin, an actin binding protein. Cadherins play important part in tumor invasion and metastasis. P-cadherin is selectively expressed in basal and parabasal layers of stratified epithelia. It may be involved in the final stages of tumor progression in epidermal carcinoma. Changes in P-cadherin expression have been implicated in breast and melanocytic tumors.

Host Species: Mouse

Clone: 56C1

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: External domain

Immunogen: Recombinant protein corresponding to extracellular domain of human cadherin-P

Molecular Weight: 120kDa

Positive Control: Skin

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: IVD; Int'l: IVD

Specifications

Antigen Cadherin-P/P-cadherin Ab-1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 56C1
Conjugate Unconjugated
Host Species Mouse
Immunogen Recombinant protein corresponding to extracellular domain of human P-cadherin
Purification Method Skin
Quantity 100 μL
Regulatory Status RUO
Research Discipline Junction Protein
Primary or Secondary Primary
Target Species Human
Form Supernatant
Isotype IgG1
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