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MilliporeSigma™ Calbiochem™ BzATP Triethylammonium Salt
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Quantity:
1 mg
Description
A prototypic P2X7 purinergic receptor agonist that exhibits about 3-fold higher agonistic potency for induction of nucleotide channels than ATP (EC50 = 15μM vs 50μM). Serves as a photo-affinity analog of ATP. Its agonistic activity is significantly reduced in the presence of serum albumin. Can serve as a substrate analog for submitochondrial particle ATPase activity (Km = 940μM). Induces a dose-dependent decrease in wild-type murine neural progenitor cell viability and an increase in caspase-3 activity. These effects are not observed in P2X7-/- mice.

Specifications
Specifications
Quantity | 1 mg |
Solubility | H2O |
Molecular Formula | C24H24N5O15P3·3C6H15N |
Physical Form | Solid |
Color | White |
Purity | 98% by HPLC |
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