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Calcipotriol, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Calcipotriol is a vitamin D3 analog that displays minimal effects on calcium homeostasis. Regulates cell differentiation and proliferation; exhibits antiproliferative activity against human HL-60, HL60/MX2, keratinocytes, MCF-7, T47D, SCC-25, and mouse WEHI-3 cancer cell lines. Calcipotriol suppresses skin cancer development in mice in a thymic stromal lymphopoietin (TSLP)-dependent manner. Calcipotriol promotes the differentiation of keratinocytes. In human T cells and in psoriatic skin, Calcipotriol increases IL-10 secretion, induces secretion of type 2 cytokines by T cells and modulates the differentiation of dendritic cells and T cells.
Specifications
Quantity | 10 mg |
Formula Weight | 412.6 |
Percent Purity | >98% |
Chemical Name or Material | Calcipotriol |
Safety and Handling
Recommended Storage : Desiccate at -20°C
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