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  5. Tocris Bioscience™ Calcipotriol

Tocris Bioscience™ Calcipotriol
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Catalog No. 270010
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Vitamin D3 analog

Calcipotriol is a vitamin D3 analog that displays minimal effects on calcium homeostasis. Regulates cell differentiation and proliferation; exhibits antiproliferative activity against human HL-60, HL60/MX2, keratinocytes, MCF-7, T47D, SCC-25, and mouse WEHI-3 cancer cell lines. Calcipotriol suppresses skin cancer development in mice in a thymic stromal lymphopoietin (TSLP)-dependent manner. Calcipotriol promotes the differentiation of keratinocytes. In human T cells and in psoriatic skin, Calcipotriol increases IL-10 secretion, induces secretion of type 2 cytokines by T cells and modulates the differentiation of dendritic cells and T cells.

Chemical Identifiers

CAS 112965-21-6
Molecular Formula C27H40O3

Specifications

Quantity 10 mg
Formula Weight 412.6
Purity >98%
Molecular Weight (g/mol) 412.61
Chemical Name or Material Calcipotriol

Safety and Handling

Recommended Storage Desiccate at -20°C
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