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Caldesmon/CALD1 Antibody (CALD1/1424R), DyLight 594, Novus Biologicals™
SDP

Catalog No. NB007977 Shop All R&D Systems Products
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NB007977 0.1 mL
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Catalog No. NB007977 Supplier Novus Biologicals Supplier No. NBP254311DL594
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Description

Rabbit Monoclonal Antibody

Caldesmon/CALD1 Monoclonal specifically detects Caldesmon/CALD1 in Human, Rat samples. It is validated for Western Blot.

Specifications

Antigen Caldesmon/CALD1
Applications Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone CALD1/1424R
Conjugate DyLight 594
Dilution Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias CAD, caldesmon, caldesmon 1, CDMH-CAD, HCAD, LCAD, L-CAD, MGC21352, NAG22
Gene Symbols CALD1
Host Species Rabbit
Immunogen Recombinant human full-length Caldesmon/CALD1 protein (Uniprot: Q05682 )
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cell Biology, Cellular Markers, Phospho Specific
Primary or Secondary Primary
Test Specificity Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120 150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70 80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This monoclonal antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Target Species Human, Rat
Content And Storage Store at 4°C in the dark.
Isotype IgG
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