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Tocris Bioscience™ Calphostin C
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Catalog No. 1626100U
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100 μg
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Catalog No. Quantity
16-261-00U 100 μg
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Catalog No. 16-261-00U Supplier Tocris Bioscience™ Supplier No. 1626/100U
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Description

Potent, selective and photo-dependent PKC inhibitor

Potent, selective and photo-dependent inhibitor of protein kinase C that targets the regulatory domain (IC50 = 50 nM). Displays > 1000-fold selectivity over other protein kinases such as cAMP-dependent protein kinase and tyrosine-specific protein kinase. Inhibits cell proliferation of malignant glioma cells in light-treated conditions in vitro (IC50 ∽ 40 - 60 nM). Also an antagonist of the Tcf/β-catenin complex.

Chemical Identifiers

CAS 121263-19-2
Molecular Formula C44H38O14

Specifications

Quantity 100 μg
Formula Weight 790.76
Purity >98%
Molecular Weight (g/mol) 790.774
Chemical Name or Material Calphostin C

Safety and Handling

Recommended Storage Desiccate at +4°C
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