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Calponin 1 Antibody (CALP), Alexa Fluor™ 532, Novus Biologicals™
SDP

Catalog No. NP247712A32 Shop All R&D Systems Products
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NP247712A32 0.1 mL
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Catalog No. NP247712A32 Supplier Novus Biologicals Supplier No. NBP247712AF532
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Mouse Monoclonal Antibody

Calponin 1 Monoclonal specifically detects Calponin 1 in Human, Rat samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Intracellular), Immunofluorescence.

Specifications

Antigen Calponin 1
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone CALP
Conjugate Alexa Fluor 532
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias Basic calponin, calponin 1, basic, smooth muscle, Calponin H1, smooth muscle, calponins, basic, Sm-Calp, SMCCcalponin-1
Gene Symbols CNN1
Host Species Mouse
Immunogen Crude human uterus extract
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 1264
Test Specificity Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this monoclonal antibody reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
Target Species Human, Rat
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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