Calponin 1 Antibody (CALP), Novus Biologicals™

Catalog No.	Quantity
NBP24447901	0.1 mg
NBP24447900	0.02 mg
NBP24447902	0.2 mg

Catalog No. NBP24447901 Supplier Novus Biologicals Supplier No. NBP2444790.1MG

Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Calponin 1 Monoclonal specifically detects Calponin 1 in Human, Rat samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Intracellular).

Specifications

• Antigen: Calponin 1
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
• Classification: Monoclonal
• Clone: CALP
• Concentration: 0.2mg/mL
• Conjugate: Unconjugated
• Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Accession No.: P51911
• Gene Alias: Basic calponin, calponin 1, basic, smooth muscle, Calponin H1, smooth muscle, calponins, basic, Sm-Calp, SMCCcalponin-1
• Gene Symbols: CNN1
• Host Species: Mouse
• Immunogen: Crude human uterus extract
• Molecular Weight of Antigen: 34 kDa
• Purification Method: Protein A or G purified
• Quantity: 0.1 mg
• Regulatory Status: RUO
• Research Discipline: Cancer, Cytoskeleton Markers
• Primary or Secondary: Primary
• Gene ID (Entrez): 1264
• Test Specificity: Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
• Target Species: Human, Rat
• Content And Storage: Store at 4C.
• Form: Purified
• Isotype: IgG1 κ

For Research Use Only