CAMK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 137301AP150UL

Catalog No. 50-172-8966

Description

The antibody 13730-1-AP recognizes all the members of CAMK2 family.

The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+/calmodulin (CaM) binding and autophosphorylation and has been implicated in regulation of the cell cycle and transcription. It is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner.

Specifications

• Antigen: CAMK2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAMK2A
• Gene Alias: CaM kinase II subunit alpha, CaMK II subunit alpha, CAMK2, CAMK2A, CAMK2B, CAMK2D, CAMK2G, CAMKA, CaMKII alpha, KIAA0968
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 108058, 12322, 12323, 12325, 171140, 24245, 24246, 25400, 815, 816, 817, 818
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.15 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P28652, Q13554, Q13555, Q9UQM7
• Gene Symbols: CAMK2A, CAMK2B, CAMK2D, Camk2g
• Immunogen: CAMK2 Fusion Protein Ag4745
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG