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Invitrogen™ Carbonic Anhydrase XI Polyclonal Antibody
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Catalog No. PIPA5103704
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PIPA5103704 100 μL
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Catalog No. PIPA5103704 Supplier Invitrogen™ Supplier No. PA5103704
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CA11.

Carbonic Anhydrase XI (CA11, CA XI) is a member of the carbonic anhydrases (CAs) family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Carbonic Anhydrase XI participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. Further, Carbonic Anhydrase XI show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Carbonic Anhydrase XI
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CA11
Gene Accession No. O70354, O75493
Gene Alias CA11; Car11; carbonic anhydrase 11; carbonic anhydrase XI; carbonic anhydrase-related protein 11; Carbonic anhydrase-related protein 2; carbonic anhydrase-related protein XI; carbonic anhydrase-related XI protein; CA-RP II; CARP XI; CA-RP XI; Carp2; CARP-2; CARPX1; CAR-XI; CA-XI; UNQ211/PRO237
Gene Symbols CA11, Car11
Host Species Rabbit
Immunogen A synthesized peptide derived from human CA11(Accession O75493), corresponding to amino acid residues Q274-V324.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12348, 308588, 770
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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