Invitrogen™ Carboxypeptidase E Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109581

Catalog No. PIPA5109581

Description

Immunogen sequence: PYDETRSGSA HEYSSSPDDA IFQSLARAYS SFNPAMSDPN RPPCRKNDDD SSFVDGTTNG GAWYSVPGGM QDFNYLSSNC FEITVELSCE KFPPEETLKT YWEDNKNSLI SYLEQIHRGV KGFVRDLQGN PIANATISVE GIDHDVTSAK DGDYWRLLIP GNYKLTASAP GYLAITKKVA VPYSPAAGVD FELESFSERK EEEKEELMEW WKMMSETLNF.

This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.

Specifications

• Antigen: Carboxypeptidase E
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CPE
• Gene Alias: CARBE; Carboxypeptidase E; carboxypeptidase H; CarboxypeptidaseE; CarboxypeptidaseH; CBPE; cobalt-stimulated chromaffin granule carboxypeptidase; CPE; CPH; Cph 1; Cph1; Cph-1; enkephalin convertase; fat; insulin granule-associated carboxypeptidase; prohormone-processing carboxypeptidase; R74677; si:ch211-198g9.2; unnamed protein product; zgc:85981
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12876, 1363
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.68 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P16870, Q00493
• Gene Symbols: CPE
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 257-476 of human CPE (NP_001864.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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