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CASC5 Polyclonal Antibody, Bethyl Laboratories

Catalog No. p-7140437
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50-155-8491 20 μL
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Catalog No. 50-155-8491 Supplier Bethyl Laboratories, Inc Supplier No. A300805AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Required for attachment of the kinetochores to the spindle microtubules. Directly links BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore.

Specifications

Antigen CASC5
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene KNL1
Gene Accession No. Q8NG31
Gene Alias Protein CASC5, Cancer susceptibility candidate gene 5 protein homolog, Kinetochore-null protein 1, Casc5, Knl1
Gene Symbols KNL1
Host Species Rabbit
Immunogen Between 300 and 350
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57082
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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