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Caspase 1/p20/p10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 229151AP

Catalog No. 50-173-3966


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Description

Description

22915-1-AP can recognize all five isoforms of caspase 1. It also recognizes p45 procaspase and the mature fragments p10 and p20.

Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1-b and IL-18. Caspase-1 was initially identified as an IL-1-b-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts.
Specifications

Specifications

Caspase 1/p20/p10
0.35 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P29452, P29466, P43527
CASP 1, CASP1, Caspase 1, Caspase 1/p20/p10, Caspase1, ICE, IL 1 beta converting enzyme, IL 1BC, IL1BC, IL1BCE, Interleukin 1 beta convertase, p10, p20, P45
Rabbit
IgG
150 μL
-20°C
Primary
12362, 25166, 834
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
CASP1
Liquid
Casp1
Caspase 1/p20/p10 Fusion Protein Ag11143
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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