Cathepsin K Monoclonal Antibody (C1), Invitrogen™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA543914	Invitrogen™ MA543914	20 μL
PIMA543913	Invitrogen™ MA543913	100 μL

Description

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.

Specifications

• Antigen: Cathepsin K
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Alias: AI323530; Cat K; cathepsin K; Cathepsin O; cathepsin O1; cathepsin O2; Cathepsin X; catK; CTS02; CTSK; CTSO; CTSO1; CTSO2; MGC23107; minisatellite 10q detected by probe MMS10; MMS10-Q; Ms10q; PKND; PYCD
• Gene Symbols: CTSK
• Isotype: IgG2b κ
• Purification Method: Protein A/G
• Product Type: Antibody

• Clone: C1
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Mouse, Rat, Pig
• Gene Accession No.: O35186, P43235, P55097, Q9GLE3
• Gene ID (Entrez): 13038, 1513, 29175, 397569
• Immunogen: Ala115-Met329 (Accession P43235), with N-terminal His Tag.
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: CTSK