CC2D1A Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-155-7292	Bethyl Laboratories, Inc A300285AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses (By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.

Specifications

• Antigen: CC2D1A
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: Akt kinase-interacting protein 1, five prime repressor element under dual repression-binding protein 1, five repressor element under dual repression-binding protein 1, FLJ20241, FRE under dual repression-binding protein 1, FREUD-1, Freud-1/Aki1, mental retardation, nonsyndromic, autosomal recessive, 3, MRT3, putative NF-kappa-B-activating protein 023N, putative NFkB activating protein
• Immunogen: Between 1 and 50
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: CC2D1A

• Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q6P1N0, Q8K1A6
• Gene ID (Entrez): 212139, 54862
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody