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CCBE1 Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 244491AP

Catalog No. 50-173-4365


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Description

Description

The gene encoding CCBE1 (Collagen and calcium-binding EGF domain-containing protein 1) is located on chromosome 18 in a region that is frequently found to be deleted in breast and prostate cancers. CCBE1 is a 406 amino acid secreted protein that contains two collagen-like domains and one calcium-binding epidermal growth factor (EGF-like) domain. In general, EGF-like domains include six cysteine residues that are usually involved in disulfide bonds. Calcium-binding EGF-like domains are subject to amino acid substitutions that disrupt their structure or calcium affinity, therefore altering protein function. Downregulation of the gene encoding CCBE1 is observed with high frequency in breast cancer, suggesting that loss of CCBE1 results in changes in cell adhesion and mobility due to its characterization as an extracellular protein. There are three named isoforms of CCBE1 which are produced as a result of alternative splicing events.
Specifications

Specifications

CCBE1
0.45 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q6UXH8
CCBE1, Full of fluid protein homolog, KIAA1983
Rabbit
IgG
150 μL
-20°C
Primary
147372
Western Blot
Unconjugated
CCBE1
Liquid
CCBE1
CCBE1 Fusion Protein Ag19686
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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