Invitrogen™ CCR8 Recombinant Rabbit Monoclonal Antibody (9N1Y1)

Catalog No.	Quantity
PIMA535476	100 μL

Catalog No. PIMA535476 Supplier Invitrogen™ Supplier No. MA535476

Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: FWVPFNVVLF LTSLHSMHIL DGCSISQQLT YATHVTEIIS FTHCCVNPVI YAFVGEKFKK HLSEIFQKSC SQIFNYLGRQ MPRESCEKSS SCQQHSSRSS SVDYIL.

CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. CCR8 expression has been reported in spleen and thymus, natural-killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes.

Specifications

• Antigen: CCR8
• Applications: ELISA, Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: 9N1Y1
• Concentration: 0.8 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: CCR8
• Gene Accession No.: P51685, P56484
• Gene Alias: C-C; CC chemokine receptor 8; CC chemokine receptor CHEMR1; C-C chemokine receptor type 8; C-C CKR-8; C-C motif chemokine receptor 8; CC-chemokine receptor chemr1; CC-CKR-8; CCR8; CCR-8; cd198; CDw198; chemokine (C-C motif) receptor 8; chemokine (C-C) receptor 8; chemokine (C-C) receptor-like 2; chemokine receptor-like 1; CKR-8; CKRL1; CKR-L1; Cmkbr8; CMKBRL2; CY6; GPRCY6; GPR-CY6; mCCR8; MGC129966; MGC129973; TER1
• Gene Symbols: CCR8
• Host Species: Rabbit
• Immunogen: Synthetic peptide.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1237, 12776
• Target Species: Human, Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG