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CD117/c-kit Mouse anti-Human, Clone: C117/370 + KIT/982 + KIT/983, Novus Biologicals™
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Catalog No. NBP247845B Shop All R&D Systems Products
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NBP247845B 0.2 mg
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Catalog No. NBP247845B Supplier Novus Biologicals Supplier No. NBP2478450.2MG

Description

Mouse Monoclonal Antibody

CD117/c-kit Monoclonal antibody specifically detects Antigen in Human samples. It is validated for Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin).

Specifications

Antigen CD117/c-kit
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Classification Monoclonal
Clone C117/370 + KIT/982 + KIT/983
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias CD117, CD117 antigen, ckit, C-Kit, EC 2.7.10, EC 2.7.10.1, PBT, piebald trait, Proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, SCFRmast/stem cell growth factor receptor, soluble KIT variant 1, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
Gene Symbols KIT
Host Species Mouse
Immunogen Recombinant human CD117 proteins
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline B Cell Development and Differentiation Markers, Cancer, Cancer Stem Cells, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid derived Suppressor Cell, Protein Kinase, Signal Transduction, Stem Cell Markers, Tyrosine Kinases
Primary or Secondary Primary
Gene ID (Entrez) 3815
Test Specificity This MAb recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
Target Species Human
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG
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