CD138 (Syndecan-1) Monoclonal Antibody (C3), Invitrogen™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA543910	Invitrogen™ MA543910	20 μL
PIMA543909	Invitrogen™ MA543909	100 μL

Description

CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.

Specifications

• Antigen: CD138 (Syndecan-1)
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Alias: AA408134; AA409076; CD antigen 138; CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; HSPG; sCD138; SDC; Sdc1; soluble CD138; Sstn; syn-1; Synd; SYND1; Synd-1; SYNDECA; syndecan; syndecan 1; syndecan proteoglycan 1; Syndecan1; syndecan-1; synstatin
• Gene Symbols: Sdc1
• Isotype: IgG1 κ
• Purification Method: Protein A/G
• Product Type: Antibody

• Clone: C3
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: P18827
• Gene ID (Entrez): 6382
• Immunogen: Gln23-Leu253 (Accession P18827), with N-terminal His and GST Tag.
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: Sdc1