CD19 Antibody (CVID3/429) - Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2619090.1MG

Catalog No. NBP26190901

Description

CD19 Monoclonal specifically detects CD19 in Human, Monkey, Chimpanzee samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, CyTOF-ready.

Specifications

• Antigen: CD19
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Dilution: Flow Cytometry 0.5 - 1 μg/million cells in 0.1 ml, Immunocytochemistry/Immunofluorescence 0.5 - 1.0 μ/mL
• Gene Alias: B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19 antigen, CD19 molecule, CVID3, Differentiation antigen CD19, MGC12802, T-cell surface antigen Leu-12
• Host Species: Mouse
• Quantity: 0.1 mg
• Gene ID (Entrez): 930
• Target Species: Human, Monkey, Primate
• Isotype: IgG1 κ

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
• Clone: CVID3/429
• Conjugate: Unconjugated
• Formulation: 10 mM PBS with no preservative
• Gene Symbols: CD19
• Immunogen: Recombinant human CD19 protein
• Primary or Secondary: Primary
• Test Specificity: CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is present in both benign and malignant B-cells and is considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue, CD19 is observed in germinal centers, in mantle zone cells, and in scattered cells of the inter-follicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However, in contrast to CD20, expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. Anti-CD19 positivity is seen in the vast majority of B-cell neoplasms commonly at a lower intensity than normal B-cell counterparts. Plasma cell neoplasms are nearly always negative, as are T-cell neoplasms
• Content And Storage: Store at 4°C.