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  6. Invitrogen™ CD197 (CCR7) Monoclonal Antibody (3D12), Brilliant Violet™ 421, eBioscience™, Invitrogen™ 

Invitrogen™ CD197 (CCR7) Monoclonal Antibody (3D12), Brilliant Violet™ 421, eBioscience™, Invitrogen™

Catalog No. p-7250724
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Catalog No. Quantity
40-419-7941 25 Tests
40-419-7942 100 Tests
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Catalog No. 40-419-7941 Supplier Invitrogen™ Supplier No. 404197941
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Description

Rat Monoclonal Antibody

CCR7 is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains and functions as a receptor for 6Ckine/SLC (secondary lymphoid-tissue chemokine), CCL19 and CCL21. CCR7 has been shown to be internalized via clathrin-coated pits and the majority recycled back to the plasma membrane. CCR7 is expressed on T cells and can be used to distinguish populations of naive from central and effector memory T cells. CCR7 has been shown to play a role in migration of memory T cells to inflamed tissue. Expression of CCR7 is also found on DC's. During DC maturation CCR7 expression increases and is thought to be involved in a variety of functions: chemotaxis to the lymph node, cellular architecture, rate of endocytosis, survival and maturation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD197 (CCR7)
Applications Flow Cytometry
Classification Monoclonal
Clone 3D12
Concentration 5 μL/Test
Conjugate Brilliant Violet 421
Formulation PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Ccr7
Gene Accession No. P32248
Gene Alias BLR2; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; C-C chemokine receptor type 7; C-C CKR-7; C-C motif chemokine receptor 7; CC-CKR-7; CCR7; CCR-7; CD197; CDw197; chemokine (C-C motif) receptor 7; chemokine (C-C) receptor 7; Cmkbr7; EBI1; Ebi1h; EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced gene 1; Epstein-Barr virus-induced G-protein coupled receptor 1; EVI1; lymphocyte-specific G protein-coupled peptide receptor; MIP-3 beta receptor
Gene Symbols Ccr7
Host Species Rat
Purification Method Affinity chromatography
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1236
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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