CD1b Antibody (RIV12), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2329250.1MG

Catalog No. NBP232925A

Description

CD1b Monoclonal specifically detects CD1b in Human samples. It is validated for Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence.

Specifications

• Antigen: CD1b
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Alias: CD1, CD1A, CD1b antigen, CD1B antigen, b polypeptide, CD1b molecule, cortical thymocyte antigen CD1B, differentiation antigen CD1-alpha-3, MGC125990, MGC125991, R1, T-cell surface glycoprotein CD1b
• Host Species: Mouse
• Molecular Weight of Antigen: 49 kDa
• Quantity: 0.1 mg
• Research Discipline: Immunology
• Gene ID (Entrez): 910
• Target Species: Human
• Form: Purified

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
• Clone: RIV12
• Dilution: Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml
• Gene Accession No.: P29016
• Gene Symbols: CD1B
• Immunogen: Human peripheral lymphocytes
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: The mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ