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CD2 Antibody (1E7E8.G4), Novus Biologicals™
SDP

Catalog No. NBP232814A Shop All R&D Systems Products
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0.1 mg
0.2 mg
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Catalog No. Quantity
NBP232814A 0.1 mg
NBP232814F 0.02 mg
NBP232814B 0.2 mg
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Catalog No. NBP232814A Supplier Novus Biologicals Supplier No. NBP2328140.1MG
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Description

Mouse Monoclonal Antibody

CD2 Monoclonal specifically detects CD2 in Human samples. It is validated for Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Functional.

Specifications

Antigen CD2
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
Classification Monoclonal
Clone 1E7E8.G4
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P06729
Gene Alias CD2 antigen, CD2 antigen (p50), sheep red blood cell receptor, CD2 molecule, Erythrocyte receptor, FLJ46032, LFA-2, LFA-3 receptor, lymphocyte-function antigen-2, Rosette receptor, SRBC, T11, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5
Gene Symbols CD2
Host Species Mouse
Immunogen Human Thymocytes/Sezary T cells
Molecular Weight of Antigen 50 kDa
Purification Method Protein A purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Adaptive Immunity, Apoptosis, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 914
Test Specificity CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG2a κ
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