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CD2 Antibody (BH1), DyLight 488, Novus Biologicals™
SDP

Catalog No. NBP234561G Shop All R&D Systems Products
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NBP234561G 0.1 mL
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Catalog No. NBP234561G Supplier Novus Biologicals Supplier No. NBP234561G
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Description

Mouse Monoclonal Antibody

CD2 Monoclonal specifically detects CD2 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen CD2
Applications Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone BH1
Conjugate DyLight 488
Dilution Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Gene Alias CD2 antigen, CD2 antigen (p50), sheep red blood cell receptor, CD2 molecule, Erythrocyte receptor, FLJ46032, LFA-2, LFA-3 receptor, lymphocyte-function antigen-2, Rosette receptor, SRBC, T11, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5
Gene Symbols CD2
Host Species Mouse
Immunogen Human CD2 protein (Uniprot: P06729)
Molecular Weight of Antigen 50 kDa
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Adaptive Immunity, Apoptosis, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 914
Test Specificity CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
Target Species Human
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG2b κ
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For Research Use Only

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