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CD206 (MMR) Mouse anti-Human, APC, Clone: 19.2, eBioscience™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

$117.00 - $306.00

Specifications

Antigen CD206 (MMR)
Clone 19.2
Target Species Human
Conjugate APC
Isotype IgG1, kappa
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-112-3103 Non-distribution product as customer accommodation. View Documents Invitrogen
17206941
25 Tests Each for $117.00
Add to cart
 
50-112-9466 Non-distribution product as customer accommodation. View Documents Invitrogen
17206942
100 Tests Each for $306.00
Add to cart
 
Description

Description

Description: This 19.2 monoclonal antibody reacts with human CD206, which is also known as the macrophage mannose receptor (MMR). CD206 is expressed on macrophages and dendritic cells. This type I transmembrane protein can also be detected on non-immune cells, including hepatic and lymphathic epithelia and kidney mesengial cells. CD206 binds to glycoproteins that terminate in D-mannose, L-fucose, or N-acetylglucosamine, as well as a variety of hormones. This receptor undergoes constitutive internalization and recycling between the plasma membrane and the endosomal compartment. CD206 is involved in antigen processing and presentation, cell migration, and intracellular signaling. Moreover, CD206 plays a key role in phagocytosis pathogens such as Candida albicans, Leishmania, and Mycobacterium tuberculosis. Applications Reported: This 19.2 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 19.2 antibody has been pre-titrated and tested by flow cytometric analysis of stimulated normal human peripheral blood monocytes. This can be used at 5 µL (0.06 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 µm post-manufacturing filtered.

Mannose receptor, also know as CD206, is a 175kDa transmembrane protein belonging to the group of pattern recognition receptors. CD206 is predomitly expressed in tissue macrophages and dentritic cells and can also be found in a subpopulation of endothelial cells and sperm cells. CD206 is thought to play a role in the innate and adaptive immune response.
Specifications

Specifications

CD206 (MMR)
Human
IgG1, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
19.2
APC
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.

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