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CD25/IL-2R alpha Antibody (143-13), Alexa Fluor™ 750, Novus Biologicals™
SDP

Catalog No. NP24772A70 Shop All R&D Systems Products
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NP24772A70 0.1 mL
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Catalog No. NP24772A70 Supplier Novus Biologicals Supplier No. NBP247725AF750
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Description

Mouse Monoclonal Antibody

CD25/IL-2R alpha Monoclonal specifically detects CD25/IL-2R alpha in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

Specifications

Antigen CD25/IL-2R alpha
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone 143-13
Conjugate Alexa Fluor 750
Dilution Flow Cytometry, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Gene Symbols IL2RA
Host Species Mouse
Immunogen Stimulated human leukocytes
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 3559
Test Specificity Recognizes a protein of 55kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This monoclonal antibody recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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