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CD25/IL-2R alpha Antibody (143-13), Novus Biologicals™

Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP2450880.1MG
Description
Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence
CD25/IL-2R alpha Monoclonal specifically detects CD25/IL-2R alpha in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Functional, Immunofluorescence.Specifications
CD25/IL-2 R alpha | |
Monoclonal | |
0.2 mg/mL | |
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml | |
P01589, P01589 | |
IL2RA | |
Stimulated human leukocytes | |
Protein A or G purified | |
RUO | |
Primary | |
Recognizes a protein of 55kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkin's disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25. | |
Store at 4C. | |
IgG1 κ |
Flow Cytometry, SDS-Page, Immunofluorescence | |
143-13 | |
Unconjugated | |
10mM PBS and 0.05% BSA with 0.05% Sodium Azide | |
CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR | |
Mouse | |
55 kDa | |
0.1 mg | |
Adaptive Immunity, Apoptosis, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction | |
3559 | |
Human | |
Purified |
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