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  6. CD25/IL-2R alpha Antibody (Basiliximab) - Chimeric - Azide and BSA Free, Novus Biologicals™

CD25/IL-2R alpha Antibody (Basiliximab) - Chimeric - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. NBP25266102 Shop All R&D Systems Products
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0.025 mg
0.2 mg
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NBP25266102 0.2 mg
NBP25266125 0.025 mg
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Catalog No. NBP25266102 Supplier Novus Biologicals Supplier No. NBP2526610.2MG
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Description

Rabbit Monoclonal Antibody

CD25/IL-2R alpha Monoclonal specifically detects CD25/IL-2R alpha in Human, Cynomolgus Monkey, Rhesus Macaque samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunofluorescence, CyTOF-ready, Block/Neutralize.

Specifications

Antigen CD25/IL-2 R alpha
Applications Western Blot, Flow Cytometry, Immunohistochemistry, Blocking Assay, Immunofluorescence, CyTOF
Classification Monoclonal
Clone Basiliximab
Conjugate Unconjugated
Dilution Western Blot 1:100 - 1:2000, Flow Cytometry 1:10 - 1:1000, Immunohistochemistry 1:10 - 1:500, Blocking/Neutralizing 50 - 200 molar excess, Immunofluorescence 1:10 - 1:500, CyTOF-ready
Formulation PBS with 0.02% Proclin 300. with 0.02% Proclin 300
Gene Alias CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Gene Symbols IL2RA
Host Species Rabbit
Immunogen CD25
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 3559
Test Specificity Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit - binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ( alpha beta yc) - T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
Target Species Human, Mouse, Rat
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG
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