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CD275 (B7-H2) Monoclonal Antibody (MIH12), Functional Grade, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
$3270.00
Specifications
| Antigen | CD275 (B7-H2) |
|---|---|
| Clone | MIH12 |
| Concentration | 1 mg/mL |
| Applications | Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Neutralization |
| Classification | Monoclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
16-588-938
|
LIFE TECHNOLOGIES
16588938 |
5 mg |
Each of 1 for $3,270.00
|
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Description
The MIH12 MAb reacts with human B7RP-1, also known as B7h, B7-H2, GL50 and ICOS Ligand. B7RP-1, a member of the B7 family, has a predicted molecular weight of approximately 40 kDa and belongs to the Ig superfamily. Human B7RP-1 is expressed by activated monocytes/macrophages. B7RP-1 binds to the ICOS molecule (AILIM, CRP-1) expressed by activated T cells. The interaction of ICOS/B7RP-1 plays an important role in the T cell costimulation pathway.
Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.Specifications
| CD275 (B7-H2) | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with no preservative; pH 7.2 | |
| AU044799; B7 homolog 2; B7 homologue 2; B7h; B7H2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP1; B7RP-1; BG071784; CD275; GI50; GL50; GL50-B; ICOS ligand; ICOSL; ICOS-L; ICOSLG; inducible T-cell costimulator ligand; inducible T-cell co-stimulator ligand; KIAA0653; LICOS; Ly115l; mKIAA0653; RGD1562791; transmembrane protein B7-H2 ICOS ligand | |
| IgG1 κ | |
| Affinity Chromatography | |
| Antibody |
| MIH12 | |
| Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Neutralization | |
| Functional Grade | |
| Mouse | |
| Human | |
| O75144 | |
| 23308 | |
| Primary | |
| 4°C | |
| ICOSLG |
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