CD28 Antibody (204.12), DyLight 755, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP254769IR

Catalog No. NBP254769IR

Description

CD28 Monoclonal specifically detects CD28 in Human, Mouse, Porcine, Bovine, Sheep samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

Specifications

• Antigen: CD28
• Classification: Monoclonal
• Conjugate: DyLight 755
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: CD28
• Immunogen: Stimulated human leucocytes
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG2a κ

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
• Clone: 204.12
• Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence
• Gene Alias: CD28 antigen, CD28 antigen (Tp44), CD28 molecule, MGC138290, T-cell-specific surface glycoprotein CD28, Tp44
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Adaptive Immunity, Apoptosis, Cancer, Cell Biology, Immune System Diseases, Immunology, Neuroscience, Signal Transduction
• Gene ID (Entrez): 940
• Target Species: Human, Mouse, Pig, Primate, Sheep
• Form: Purified