CD3 epsilon Antibody (APA1/1), DyLight 488, Novus Biologicals™

Catalog No.	Quantity
NBP130426G	0.1 mL

Catalog No. NBP130426G Supplier Novus Biologicals Supplier No. NBP130426G

Description

Mouse Monoclonal Antibody

CD3 epsilon Monoclonal specifically detects CD3 epsilon in Human, Mouse samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen.

Specifications

• Antigen: CD3 epsilon
• Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
• Classification: Monoclonal
• Clone: APA1/1
• Conjugate: DyLight 488
• Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
• Gene Alias: CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, FLJ18683, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE
• Gene Symbols: CD3E
• Host Species: Mouse
• Immunogen: Purified human CD3 proteins isolated from thymus
• Purification Method: Protein A purified
• Quantity: 0.1 mL
• Regulatory Status: RUO
• Research Discipline: Adaptive Immunity, Apoptosis, Diabetes Research, Immunology, Innate Immunity, Signal Transduction
• Primary or Secondary: Primary
• Gene ID (Entrez): 916
• Test Specificity: The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
• Target Species: Human, Mouse
• Content And Storage: Store at 4C in the dark.
• Form: Purified
• Isotype: IgG1

For Research Use Only